The campers were kicked out of Granthams Bend in Wahgunyah on Wednesday morning, with one of the five having stayed there for a few months.

Camping grounds are off limits as part of COVID-19 restrictions.

A man was caught driving erratically in Chiltern in the early hours of Tuesday and was fined $1652.

A Mt Beauty man was also busted travelling to his friend's home on Monday morning and given a penalty notice.

He told officers he had been attending the home to pick up some toilet paper, but a check showed he didn't need any.

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Police are urging drivers to stay at home as much as possible over Easter in a bid to prevent the spread.

Wodonga Inspector Paul Hargreaves said multiple people had flouted the restrictions.

"We have been reasonably flexible insofar as people trying to do the right thing, or for those who were a bit unsure," he said.

"It's been quite clear to us where we have had to issue penalty notices - where they're blatantly ignoring what the rules are.

"Where people are congregating in groups of more than two people, with no reason other than drinking or having a get together, they're the ones that concern us.

"They know you should not be with more than one person.

"Some people are saying 'I'm not going to follow that rule'."

Police have handed out at least six fines in the Albury region.

"Those who show blatant disregard may find themselves with a $1000 on the spot fine or $5000 on the spot fine for a business, or before the courts to answer for their actions," Superintendent Paul Smith said

Those caught were undertaking other illegal activity, he said.

While restrictions vary slightly between Victoria and NSW, people are generally only allowed to go to work, medical appointments, shop for essential items and exercise.

Inspector Hargreaves said police were receiving information about those breaching the requirements.

"They're worried about the consequences of that," he said.

"We are supportive of that and are certainly happy to take calls.

"The public have, in the main, been very compliant and supportive."

Police on both sides of the border are running road safety operations from Friday morning until Monday night.

North East Senior Sergeant Darren Wittingslow discouraged people from non-essential activities.

"Police will be strongly enforcing the stay at home requirements," he said.

"If people think they're going on a camping holiday, don't.

"Just stay at home.

"It's for the safety and welfare of the whole community.

"If we see cars with caravans, trailers and camping gear they will be pulled over and we will have a discussion with them."

Albury Sergeant Matt Zemaitis said double demerits would be enforced in NSW.

"Our main role is ensuring the roads are safe," he said.

"In saying that, there shouldn't be much movement on roads over the Easter period.

"You're very limited in why you can travel."