Wales will impose a two-week "fire-break" lockdown in which everybody apart from essential workers must stay at home to combat an accelerating second wave of COVID-19.
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Welsh First Minister Mark Drakeford said he understood that people were tired of coronavirus restrictions but tougher rules were essential as critical care units were already full.
"It will have to be sharp and deep in order to have the impact we need," Drakeford told reporters.
"Everyone in Wales will be required to stay at home."
"If we do not act now, it will continue to accelerate."
The lockdown will begin on Friday at 1700 GMT and end on November 9.
Everybody but essential workers will have to work from home.
All non-essential retail, leisure, hospitality and tourist businesses will have to close in Wales, as will places of worship.
Most children apart from some older students will return to school in the second week after the half-term holiday.
Business affected will be supported by a 300 million pound ($A549 million) fund, Drakeford said.
The United Kingdom recorded 16,982 new daily cases of COVID-19 in the space of 24 hours, according to government data issued on Sunday, up from 16,717 the previous day.
Wales recorded 950 cases, up from just 400 at the start of the month.
All four nations of the United Kingdom are recording a resurgence of COVID-19, and devolved governments and local councils are introducing a range of measures to try to stem the rise.
Northern Ireland started a four-week period of tougher curbs on Friday, while Scotland has imposed new rules for hospitality.
Australian Associated Press
