Target will cease to exist in Corowa from April when the department store closes up the country branded shop.
Parent company Wesfarmers made the decision to close up to 75 Target stores across the country, with another 92 converted to Kmart outlets.
A Target spokesperson confirmed the Sanger Street store will close in April, but a definite date was not yet set.
The Deniliquin store will close on March 27.
IN OTHER NEWS:
"We want to thank our Deniliquin and Corowa team, the local community and all of our customers for shopping with us over the years," a spokesperson said.
"Our focus is on supporting our team through this time as we work through finding suitable redeployment within other Wesfarmers businesses as well as with other employers in town.
"Any permanent team members who we are unable to secure suitable redeployment will have access to all their entitlements."
The Benalla and Myrtleford stores are also set to close in April.