The time of year is typically dangerous with a large number of vehicles and motorbikes on the roads.

Victorian officers are running Operation Nexus from Thursday morning until Monday night, focusing on speed, drink and drug driving, fatigue, seatbelt and distraction offences.

NSW police members are running an operation over the same days with double demerit points to be enforced for offences including phone use and speeding.

Wangaratta Acting Senior Sergeant Tim Hart said North East officers were particularly concerned about motorbike riders.

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"On recent holiday weekends there were several motorcycle accidents in remote areas," he said.

"One of the main causes is riders being unaware or not responding appropriately to the road conditions.

"Conditions on remote unmade roads can change from wet to dry, from compacted to loose in a short distance."

Acting Senior Sergeant Hart said people would see more officers on the road.

"We recognise your right to have an enjoyable Easter, and as we move into what is loosely termed Covid-normal, the local businesses and tourist operators are eager to have visitors back, but we all need to take responsibility for our own safety on the road," he said.

All drivers stopped by police will be breath tested.

There were no deaths in the Albury-Wodonga region last Easter with traffic reduced due to coronavirus restrictions.

But officers did detect a range of offences, including a car hitting 150km/h on Wagga Road and drink drivers.

Albury Inspector Scott Trewhella urged people to look out for one another this long weekend.

"We will continue to place a strong focus on the Four Ds: drink, drug, dangerous and distracted driving," he said.

"Road safety is always a priority, but even more so on long weekends when we see more people travelling throughout our region.

"If you see something dangerous on our roads, we want to know about it."

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