One in three COVID-19 survivors in a study of more than 230,000 mostly American patients were diagnosed with a brain or psychiatric disorder within six months, suggesting the pandemic could lead to a wave of mental and neurological problems, scientists say.
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Researchers who conducted the analysis say it's not clear how the virus is linked to psychiatric conditions such as anxiety and depression, but these were the most common diagnoses among the 14 disorders they looked at.
Post-COVID cases of stroke, dementia and other neurological disorders were rarer but were still significant, especially in those who had severe COVID-19.
"Our results indicate that brain diseases and psychiatric disorders are more common after COVID-19 than after flu or other respiratory infections," said Max Taquet, a psychiatrist at Britain's Oxford University, who co-led the work.
The study was not able to determine the biological or psychological mechanisms involved, he said, and urgent research was needed to identify these "with a view to preventing or treating them".
Health experts are increasingly concerned by evidence of higher risks of brain and mental health disorders among COVID-19 survivors. A previous study by the same researchers found last year that 20 per cent of COVID-19 survivors were diagnosed with a psychiatric disorder within three months.
The new findings, published in the Lancet Psychiatry journal, analysed health records of 236,379 COVID-19 patients, mostly from the United States, and found 34 per cent had been diagnosed with neurological or psychiatric illnesses within six months.
The disorders were significantly more common in COVID-19 patients than in comparison groups of people who recovered from flu or other respiratory infections over the same time period, the scientists said, suggesting COVID-19 had a specific impact.
Anxiety, at 17 per cent, and mood disorders, at 14 per cent, were the most common, and did not appear to be related to how mild or severe the patient's COVID-19 infection had been.
Among those who had been admitted to intensive care with severe COVID-19 however, seven per cent had a stroke within six months, and almost two per cent were diagnosed with dementia.
"Although the individual risks for most disorders are small, the effect across the whole population may be substantial," said Paul Harrison, an Oxford psychiatry professor who co-led the work.
Australian Associated Press
