Businesses, including Pirates Treasure House outlets in Yarrawonga and Barooga, were searched by multiple police agencies and the Australian Border Force.

Illegal loose leaf tobacco and cigarettes were seized, along with smoking paraphernalia and other materials.

Detective Sergeant Marcus Boyd said a "significant" amount of property had been seized.

Multiple people were questioned but charges haven't been laid.

Police are investigating possible tobacco importation and excise offences.

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"A number of people have been spoken to," Detective Sergeant Boyd said.

"Investigations are continuing.

"We're looking at offences in breach of the Customs Act."

Officers from Cobram, Yarrawonga, Wangaratta, and NSW Police joined the Australian Border Force during the search warrants, which started at 6am.

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