Myrtleford's Standish Street Surgery is among medical practices preparing to inoculate with Pfizer as the vaccine becomes available to a wider age range.
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Practice manager Kerri Bray said AstraZeneca jabs continued and from July 5, Pfizer would be available.
"We have one vaccination clinic booked for Pfizer," she said.
"We would like to encourage more people aged 40 to 59 to call us to book in an appointment as we have additional capacity at this stage.
"Nevertheless, we are only able to accept bookings from people who live within the Myrtleford catchment."
Vaccines will arrive thawed and expire within 31 days of arrival, compared to AstraZeneca's six-month expiry.
Ms Bray, whose team is vaccinating in a building at the Myrtleford RSL, said supply had exceeded demand.
"Our main issue has always been vaccine hesitancy, not supply," she said.
"We commenced AstraZeneca on March 22 and we have had no problems with supply.
"We have increased our administration and clinical staff to cope with logistics of running these vaccinations clinics; the whole team has worked together very well.
"We are extremely grateful to have the RSL's support."
Ms Bray urged people to speak with a GP if they were concerned about the jab.
"Make an appointment to get vaccinated and do your part to protect the community," she said.
Currently, state hubs remain the only way to access the Pfizer vaccine, and bookings for initial vaccinations are paused.
But a small number of GPs in the North East and Southern NSW will begin to offer Pfizer from July 5, with more sites to be added.
The Commonwealth's vaccine eligibility tracker will be updated to reflect those clinics with Pfizer closer to July 5.
The Murray Primary Health Network is encouraging more practices to submit expressions of interest to participate in the Pfizer vaccination program, with those based in rural locations being prioritised.
Federal Health Minister Greg Hunt outlined from July 5, there would be a progressive on-boarding of up to 500 general practices to provide the Pfizer vaccine for people aged 40 to 59.
"This will then expand up to a further 500 in the week commencing July 12, and then up to a further 300 in the week commencing July 19," he said.
AstraZeneca remains recommended for those aged 60 and over based on the much higher risk of illness and death from COVID-19 in this age group, and the lower risk of very rare blood-clotting thrombosis with thrombocytopenia syndrome.
"The updated medical advice is made with an abundance of caution, noting that the U.K. provides for AstraZeneca vaccines for those 40 and above, South Korea for 30 and above, and Germany has no restrictions," Mr Hunt said.
Albury Wodonga Health is urging anyone who has received their first AstraZeneca dose to get their second.
"Both AWH Wodonga Hub and Northeast Health Wangaratta Hub have appointments available for second dose Pfizer and first and second AstraZeneca vaccines," a spokeswoman said.
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Meanwhile, second AstraZeneca doses have been given in all Murray PHN private residential aged care facilities, with roving clinics being organised for residents who were missed.
A free helpline (1800 312 968) has been launched by Murray PHN for Victorian health services for advice on infection control, developed with funding from the Victorian Department of Health.
