Chief executive Jill Ludford said workers should also consider wearing masks in offices to limit possible spread of the virus, despite it no longer being a requirement under NSW public health orders.

Ms Ludford confirmed just 24 per cent of eligible children are vaccinated against COVID-19 and from tomorrow the health service would be hosting a 'Kids Health Week' to help improve that rate.

"Schools are also a great concern, now we have such a great number of people who are vaccinated in our region.. the most [vulnerable] are the children aged under 12 who aren't able to be vaccinated," she said.

"We have seen quite a number of primary school aged children who have had positive cases and been transmission sources ."

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Ms Ludford said MLHD was working closely with the Department of Education and Department of Health to hopefully get at least one parent per family back to work and to minimise the isolation time for families.

"What we're really asking for children, and this is really for people under the age of 16, during this time where it is risky really have a look at extra-curricular activities, particularly indoor sport," she said.

"It's probably best if those sorts of activities can be held outdoors with people wearing masks and really limit your movements and activities to try and break some of the strains of transmission."

Ms Ludford said it was very important that the cases in Albury and Wodonga were seen as one outbreak.

She said MLHD was working jointly with NSW Health as well as Victoria's Health Department and Albury-Wodonga Health.

"We're also starting to see some seeding from this outbreak coming into the LGAs around the border region, so my message to people is this is a very very important time, we have to be vigilant," she said.

"We have been incredibly lucky in the Murrumbidgee region to date where we've had one or two isolated exposures or isolated cases. The difference now is we are seeing community transmission and that is a very big difference."

There is a growth factor larger than one in Albury-Wodonga's cases, meaning the community can continue to see case numbers rising over following days.

"As we get on top of the outbreak, get people into isolation and get more people vaccinated, then we will start to see a slow-down, and we've seen that in other communities," Ms Ludford said.

"There are a large number of people who are unwell and receiving care from Albury Wodonga Health ... it's also really important to note the low number of people in hospital.

"It's really important that we see this outbreak as one outbreak ... we are having joint planning meetings with members of the Victorian government and Albury Wodonga Health."

Ms Ludford said MLHD had not identified the original cause of the outbreak and flagged difficulty in doing so.

"It's very difficult to say where the original source case came from," she said.

"We haven't done genomic testing, so I really can't comment on where the case came from.

"But now that we have people moving around more freely across our different states, and of course, that collision of the border there ... I think it's pretty easy to see that we're going to see this sort of transmission happening more and more."

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