Yackandandah business owners have been frustrated by a spate of break-ins in the town.
Newsagency owner David Lacey said it was a blow to his business, which will now undergo security upgrades.
"It wasn't a hell of a lot of money involved," he said.
It is disappointing, it's not what you expect here at all.- David Lacey, owner of Yackandandah Newsagency
"Fortunately I'd banked that day, but I lost a day's takings and my back-up notes.
"It is disappointing, it's not what you expect here at all."
Mr Lacey said a Lord brand safe was taken, and the burglars ripped out a cash till.
"It's a bit of a wake-up call not to take security for granted," he said.
"We're a small business, but luckily most people don't pay with cash these days so there's less money to steal which is positive."
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Butcher owner Clare Cooper said such incidents were rare in Yackandandah.
"It's frustrating, our business in Beechworth got hit about two months ago, so it's a bit of a blow for it to happen again," she said.
Wodonga police are investigating the break-ins and others in the region and seek information.
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