Stocks have headed lower as investors remain cautious before the Federal Reserve's two-day policy meeting and what could be the latest central bank signal of an even faster pace of tightening just as signs of a global slowdown mount.
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Overall, the start of the week across markets began quietly, with the dollar holding above a 2-1/2 week high and government bond yields little changed after falling on Friday.
A widely watched survey showed German business morale falling more than expected in July as high energy prices and looming gas shortages push Europe's largest economy towards a recession.
US Treasury Secretary Janet Yellen said on Sunday that US economic growth was slowing but added that a recession was not inevitable. Data, however, suggests the likelihood of a downturn.
US business activity contracted for the first time in nearly two years amid persistently heated inflation and rapidly rising rates, according to another survey on Friday.
"Increased gloom about the outlook for the global economy looks likely to continue in the coming months as fears over elevated inflation, rising interest rates, and Russian gas in Europe continue to weigh on sentiment," said Mark Haefele, Global Wealth Management Chief Investment Officer at UBS.
"The risks of recession are increasing, but we recommend investors avoid positioning for any single scenario."
The pullback in stock prices follows a rebound in recent weeks, as investors bought back into markets that have fallen sharply in 2022 on fears of further central bank interest rate hiking, still-higher inflation and weaker economic growth.
The Euro STOXX was down 0.2 per cent in early trade on Monday, Germany's DAX 0.4 per cent lower and Britain's FTSE 0.14 per cent.
Wall Street futures pointed to a weak or flat open.
Japan's Nikkei retreated 0.77 per cent, while Chinese blue chips lost 0.6 per cent.
MSCI's World index dipped 0.2 per cent, although Monday's fall comes after it hit its highest since June 10 on Friday.
The Fed concludes a two-day meeting on Wednesday and markets are priced for a 75 basis-point rate hike, with about a nine per cent chance of a full one percentage-point increase.
Investors are on guard this week for how much a strong dollar will hurt financial results from heavyweights Apple and Microsoft, among others.
The dollar index - which measures the safe-haven currency against six major peers - was little changed at 106.61, after climbing off a 2-1/2-week low of 106.10 reached on Friday.
The 10-year US Treasury yield was little changed at 2.794 per cent after sliding from as high as 3.083 per cent over the previous two sessions.
Euro zone government bond yields rose modestly, helped by last week's bigger than expected European Central Bank rate hike and expectations there is more to follow.
Crude oil fell on concern that higher US rates would limit fuel demand growth.
Brent crude futures fell 0.6 per cent, to $US102.57 a barrel and US West Texas Intermediate crude futures dropped 0.91 per cent, to $US93.82 a barrel, both down for a fourth day.
Gold edged higher to $US1,729 per ounce.
Australian Associated Press