Update: Both southbound lanes are now open and one northbound lane is open.
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2.43pm: Drivers are being urged to avoid the Hume Highway near Tarcutta after a van erupted in flames this afternoon.
All northbound lanes of the Hume Highway are closed at Mount Adrah, around 20 kilometres north of Tarcutta, due to the fire, which has seen plumes of smoke blanket the site.
One southbound lane of the highway is also closed near the Snowy Mountains Highway.
Emergency services say there is also a fire in the centre median of the highway.
Northbound motorists already on the highway are being turned around.
Emergency services are on site, and traffic crews are responding.