Wodonga, Wangaratta, Shepparton and Seymour have been flagged as priority areas for construction of the one and two-bedroom dwellings that will be built in neighbourhoods close to services.

BeyondHousing CEO Celia Adams welcomed today's announcement and the funding commitment by Melbourne-based philanthropic group Peter and Lyndy White Foundation.

It is expected 45 homes will be built for about 100 Victorians in need of accommodation by the end of 2020.

Ms Adams said it was vital housing was delivered quickly and cost effectively to fill the gap in social housing.

The current Victorian Housing Registrar has 3644 households on the waiting list for one and two-bedroom properties in the Goulburn and Ovens Murray region.

People coming out of transitional housing, escaping family violence and those on Newstart or Youth Allowance will be able to access this housing support.

Ms Adams said safe accommodation was a basic human need.

"It's hard to get educated, it's hard to get well, it's hard to access the services you need to, it's hard to get a job ... if you don't have somewhere to live," Ms Adams said.

"I've been in and around BeyondHousing for 17 years and it is the largest philanthropic partnership in my experience in our region."

Ms Adams said BeyondHousing had "no interest in building horrible multi-storey dwellings in amongst private residential space".

"We build housing that doesn't look like social housing, that's in keeping with the environment around it, that's high quality, but also sustainable," she said.

An end date for the funding from the foundation had not been set and would be reassessed periodically with Benalla, Cobram and Yarrawonga also expected to benefit, Ms Adams said.

"We want to deliver efficiently and cost effectively and get people housed," she said.

The construction process will employ local businesses and tradespeople.

"The people that we house are part of our community so it's important that we involve the community in what we're doing," Ms Adams said.