Power out in Wodonga after car crash in Anzac Parade

Officers are still trying to piece together how the Ford sedan crossed onto the wrong side of Anzac Parade, ending up in the substation next to Blazing Stump.

Highway patrol Senior Constable Paul Marshall said it was clear the man had suffered a medical episode.

"He was conscious, a lovely young bystander heard the bang and came and helped him out of the car," he said.

"He didn't know where he was; he was taken to Albury Base Hospital.

"All drug and alcohol tests were negative.

"The possibility is he's crossed over onto the wrong side of the road, panicked and in his half-conscious state has accelerated down here and that's where he's ended up."

Senior Constable Marshall said there was a significant response from Fire and Rescue and SES given initial concerns the AusNet infrastructure has caught alight.

"The initial call was for a car on fire, person trapped," he said.

"There was a lot of smoke coming from it, but it's more that the electrical substation has an extinguisher function, for when it gets an impact like that.

"Thankfully, it wasn't major.

"Unfortunately, a bunch of these businesses will probably be without power for 12 to 24 hours, I've been told by AusNet.

"They are isolating everything else so there's no other power flowing through this, so that it's 100 per cent safe."

Police are seeking witnesses.

Senior Constable Marshall said if the man had crossed onto Wodonga-bound lanes of Anzac Parade as thought, he had missed oncoming traffic.

"He is very lucky," he said.

An Ambulance Victoria spokeswoman said a man in his 20s was taken to Albury Base Hospital, but could not provide information on his condition or injuries.

The crash has caused a major power outage with more than 1300 residents affected.

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An AustNet spokeswoman said the crash had caused extensive damage to the asset.

She said initially 2151 properties were without power, but they had been able to remotely return power to about 1191 customers.

Technicians would continue to progressively and safely return power to customers, she said, but about 275 properties will remain without power until repairs are made which could take some time.

The spokeswoman said local crews would know more once the car was removed and damage assessed.

She thanked customers for their patience and understanding and said AusNet would be regularly updating their Outage Tracker as power was restored and damage assessed.