It has been vacant since the supermarket relocated to Mann Central in 2017 and Chemist Warehouse was set to move in after purchasing the site for more than $4 million.

Vaccinations are set to start there "in coming weeks".

AWH chief executive Michael Kalimnios said interior construction was still under way at the building.

"We are excited to commence operations from the High Street location," he said.

"Until that time, initial Phase 1(a) vaccinations will be delivered at Albury Base Hospital, with the first dose due to be administered next week.

"The central location, paired with existing infrastructure and parking capacity makes it the perfect location for Albury Wodonga Health to establish its Wodonga-based vaccination hub."

The final product will consist of 36 vaccination points, two treatment rooms, two consult rooms, toilet facilities and separate rooms for pharmacy, storage and staff amenities.

The hub will also have two separate waiting areas, accommodating for individuals prior to vaccination, and those undergoing post-vaccination observation.

"The local Public Health Unit has been working through site readiness requirements to ensure the hub is compliant with Australian Government and Australian Technical Advisory Group on Immunisation (ATAGI) standards," Mr Kalimnios said.

Since AWH first announced it would deliver vaccinations for those in Alpine, Indigo, Towong, Wangaratta and Wodonga just over one month ago, preparations have been ramping up.

A 502 litre -80 degree freezer to store the Pfizer vaccine was installed last week.

As one of nine Victorian COVID-19 hospital vaccination hubs, AWH will initially vaccinate front-line healthcare workers and aged care and disability staff and residents.

AWH is working with the Murrumbidgee Local Health District on plans for the roll-out north of the border.

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Wodonga mayor Kev Poulton welcomed the announcement vaccinations would take place in the CBD.

"The hub will be regionally important in keeping our community and residents in our neighbouring council areas safe in the continuing fight against COVID-19," he said.

To see the latest information and advice about the COVID-19 vaccine in Victoria, please visit: coronavirus.vic.gov.au/vaccine or health.gov.au/initiatives-and-programs/covid-19-vaccines.

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