Residents and visitors to Moira Shire have been warned to protect themselves against Ross River fever.
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The virus has been detected in mosquitoes in the area and health authorities confirmed there is an increased risk people living in or travelling through could be infected.
Victorian Chief Health Officer Brett Sutton said mosquito numbers are high along parts of the Murray River and weather conditions are favourable for biting and breeding.
"The best protection from Ross River virus and other mosquito-borne diseases is to avoid mosquito bites," he said.
"Protective measures include regularly using mosquito repellent on all exposed skin, wearing long, loose fitting clothing when outside, and ensuring accommodation, including tents, are properly fitted with mosquito nettings or screens.
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"These viruses can cause symptoms including joint pain and stiffness, headache, fever, rash and fatigue.
"Doctors should consider the possibility of mosquito-borne disease in patients who present with a compatible illness, especially after travel to rural or regional Victoria."
Symptoms of Ross River fever can take three to nine days to occur after exposure, and sometimes up to three weeks, with rest recommended in the early stages.
A blood test early in the illness can help to identify a potential infection and should be repeated two weeks later.
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