The 24-year-old Victorian, who police say later returned a positive result for methamphetamine in a roadside drug test, came to the attention of patrolling Griffith officers on the Sturt Highway.

He was allegedly detected travelling at 150kmh on the 110kmh highway west of Hay around 9.30am on Friday, December 29.

However, instead of stopping when police hit their warning lights, the green 2006 Ford Falcon allegedly sped off.

Police began a pursuit of the vehicle, which they say reached 220kmh before the chase ultimately ended 18 kilometres later in Hay.

Despite bearing South Australia registration plates, the Falcon was not registered and the driver was a disqualified learner from Victoria.

"(The driver) tested positive for methamphetamine during a roadside drug test," police said.

"Additionally, a knife was discovered in the vehicle."

Further testing results are pending.

The man was charged with driving while disqualified and dangerous driving and not stopping in a police pursuit. He is not to occupy the driver's seat of a vehicle, police said, and is due before Hay Local Court in February.

He was also issued fines for speeding, driving an unregistered vehicle, and knife offences.

Police in both Victoria and NSW have been conducting road safety campaigns over the Christmas and New Year period.

Victoria's Operation Roadwise began on December 15 and will run for 18 days.